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An Introduction to Population Genetics Theory James F. Crow, Motoo Kimura
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The idea behind this software is that you input the genetic data for a group of people, and the program determines the relative contribution of hypothetical “parent” populations to each individual's genome. Lewontin, Richard Charles (1929-), an American evolutionary geneticist, introduced the study of molecular population genetics in the 1960's. I'll remember him for several things, the foremost being his fantastic textbook with Motoo Kimura: An Introduction to Population Genetics Theory, the book that taught me the theory underlying evolutionary genetics. Prerequisite(s): Either ST218/219 Mathematical Statistics A&B or ST220 Introduction to Mathematical Statistics. Let's look at some examples: Click to enlarge. Content: Three self-contained sets of ten lectures. The K=2 at the bottom means that this plot was generated Now we have K=3, so three theoretical parent populations. The Wright-Fisher model and the Moran model will be described but Coalescent theory will constitute the core of the course. The fourth major figure in theoretical population genetics, Motoo Kimura, was originally a physicist. Its use will be illustrated by a number of applications in molecular genetics. Commitment: 10 Aims: This course introduces easy stochastic models used in population genetics.